Glial cell modulators attenuate methamphetamine self-administration in therat
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چکیده
منابع مشابه
Glial cell modulators attenuate methamphetamine self-administration in the rat.
Neuroinflammation induced by activated microglia and astrocytes can be elicited by drugs of abuse. Methamphetamine administration activates glial cells and increases proinflammatory cytokine production, and there is recent evidence of a linkage between glial cell activation and drug abuse-related behavior. We have previously reported that ibudilast (AV411; 3-isobutyryl-2-isopropylpyrazolo-[1,5-...
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Neuroinflammation is an important component of many neuroinflammatory and neurodegenerative diseases. Microglia and astrocytes play a key role in neuroinflammation. Activated glial cells under neuroinflammatory condition produce proinflammatory cytokines, chemokines, nitric oxide (NO), and other neurotoxic mediators. Thus, it has been conventionally thought that the inhibition of such glial act...
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ژورنال
عنوان ژورنال: European Journal of Pharmacology
سال: 2013
ISSN: 0014-2999
DOI: 10.1016/j.ejphar.2013.01.016